货品编号： biolegend.302934 品 牌：biolegend 品 名：Ultra-LEAF Purified anti-human CD28 Antibody 规 格： 1mg 产品描述：

CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and

is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds

both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory

molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death.In vitrostudies indicate that ligation of

CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and

proliferation.