货品编号： BIOSS.bs-10021R-50ul 品 牌：BIOSS 品 名：Anti-NALP3/CIAS1 细胞凋亡诱导蛋白NALP3抗体 规 格： 50 µl 产品描述： 研究领域 肿瘤心血管细胞生物免疫学信号转导细胞凋亡转录调节因子 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat,Dog, 产品应用 WB=1:500-2000ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:200-800（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 114kDa 细胞定位 细胞核细胞浆分泌型蛋白 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from human Cryopyrin:15-120/1036 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍 May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of

NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity

of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of

IL1B and IL18.