货品编号： 博奥森.bs-0380R-AF555 品 牌：博奥森 品 名：AF555标记的髓鞘碱性蛋白/磷脂碱性蛋白抗体 规 格： 100ul 产品描述： 研究领域 神经生物学生长因子和激素激酶和磷酸酶 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat,Pig,Guinea Pig,G 产品应用 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 33kDa 性状 Lyophilized or Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from Gpig MBP 亚型 IgG 纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for

at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody

the antibody is stable for at least two weeks at 2-4 °C.

产品介绍

background:

The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin

membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination

of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the

early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways

in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of

them having maybe a specialized function.