货品编号： bioss.bs-1288R 品 牌：bioss 品 名：Rabbit Anti-GDF8 antibody 规 格： 50ul 产品描述： 研究领域 免疫学生长因子和激素 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Mouse,Rat, (predicted: Human,Chicken,Pig,Cow,Horse,Sheep,) 产品应用 WB=1:500-2000ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 12/43kDa 细胞定位 分泌型蛋白 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from human GDF8:281-375/375 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍 The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta

superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to

produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of

cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which

negatively regulates skeletal muscle growth. Acts specifically as a negative regulator of skeletal muscle growth.

[SUBUNIT] Homodimer; [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle. Weak

expression in adipose tissue. Belongs to the TGF-beta family.