货品编号： abclonal.A1753 品 牌：abclonal 品 名：CD3E Rabbit pAb 规 格： 50UL 产品描述： The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the

T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an

important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the

epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an

essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility

to type I diabetes in women.