货品编号： 博奥森.bs-1955R 品 牌：博奥森 品 名： 单核细胞趋化蛋白1抗体 规 格：50ul

研究领域肿瘤 细胞生物 免疫学 细胞凋亡 生长因子和激素 转录调节因子

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Rat, (predicted: Mouse, Dog, Pig, Horse, Rabbit, )

产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量11kDa

细胞定位分泌型蛋白

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human MCP-1:24-99/99

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte

anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis,

rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease

process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells

by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell

selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic

variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family.

The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor,

it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the

male signal to mainly locate the afterbirth syrup inside.