货品编号：博奥森.bs-4947R

品牌：博奥森

品名：Rabbit Anti-IL-1 Alpha antibody

规格：100ul

研究领域心血管 细胞生物 免疫学

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, (predicted: Rat, )

产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量17, 31kDa

细胞定位分泌型蛋白

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from rat IL-1 Alpha:155-230/270

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced

by certain phagocytes and auxiliary cells. Each IL acts on a specific, limited group of cells through a receptor specific

for that IL. Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes,

which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes,

but also is released from several other cell types and is thought to play a key role in inflammatory and immune responses.

The two closely related agents, interleukin 1 alpha (IL1 alpha) and interleukin 1 beta (IL1 beta) bind to the same cell surface

receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.