货品编号：Bioss.BS-4690R

品牌：Bioss

品名：CD142 Polyclonal Antibody

规格：50ul

研究领域细胞生物 生长因子和激素 细胞表面分子

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )

产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量29kDa

细胞定位细胞膜 分泌型蛋白

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Tissue factor:32-100/295 <Extracellular>

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood

coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex

provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis.

Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent

initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular,

transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency

has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]