货品编号：博奥森.bs-0107M

品牌：博奥森

品名：Mouse Anti-beta-Amyloid (1-42) antibody

规格：100ul

研究领域细胞生物 免疫学 神经生物学 Alzheimer's

抗体来源Mouse

克隆类型Polyclonal

交叉反应(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, )

产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量4.4kDa

细胞定位细胞膜

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human beta-Amyloid:1-42/42 <Cytoplasmic>

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides.

beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids.

beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor

protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last

Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides

are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid antibodies and

peptides have been developed as tools for elucidating the biology of Alzheimer's disease.