货品编号：博奥森.bs-23418R

品牌：博奥森

品名：腺苷三磷酸结合盒转运体A1抗体

规格：100ul

研究领域免疫学 信号转导 转录调节因子 转运蛋白

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, (predicted: Mouse, Rat, Pig, Cow, Horse, )

产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量254kDa

细胞定位细胞膜

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human ABCA1:1551-1650/2261 <Extracellular>

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC)

transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided

into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1

subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes.

In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human

gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.