货品编号:博奥森.bs-0345P 品牌:博奥森品名:human IgM规格:1mg 性 状Lyophilized
浓 度>1mg/ml
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least
one month and for greater than a year when kept at -20°C.
When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens
and is largely confined to plasma due to it's large size.
Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells.
Due to it's high valency IgM is more efficient than
other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating
the complement pathway. The gene for the mu constant
region contains four domains separated by short intervening sequences.
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