Biolegend.103010 PE/Cyanine5 anti-mouse/human CD44 Antibody 100ugBiolegend


货品编号: Biolegend.103010

品 牌: Biolegend

品 名: PE/Cyanine5 anti-mouse/human CD44 Antibody

规 格: 100ug

产品描述:

CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes,

endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory

stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable

marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function

via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells,

homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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