品牌：博奥森.bs-8622R

货号：博奥森

品名：核蛋白相互作用蛋白2抗体

规格：100ul

产品描述：

The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking

of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex.

Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids

or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in

different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-

sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the

NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a

role in V(D)J recombination [provided by RefSeq, Jul 2008]