博士德.BA2329 Anti-IBSP Antibody 50ul博士德-耗材-金山科研平台 Thermo Fisher官网Nunc、QSP、Nalgene、Invitrogen、Gibco耗材试剂授权一级代理

博士德.BA2329 Anti-IBSP Antibody 50ul博士德

货品编号：博士德.BA2329

品牌：博士德

品名： Anti-IBSP Antibody

规格： 50ul

货号	BA2329
产品名称	Anti-IBSP Antibody
基因名	IBSP
抗体来源	Rabbit
克隆	Polyclonal
抗体亚型	Rabbit IgG
分子量	42KD
免疫原	A synthetic peptide corresponding to a sequence at the N-terminus of human Bone Sialoprotein(17-34aa FSMKNLHRRVKIEDSEEN), different from the related rat and mouse sequences by three amino acids.
内容	500 ug/ml antibody with PBS ，0.02% NaN3 , 1 mg BSA and 50% glycerol.
纯化方式	Immunogen affinity purified.
浓度	500 ug/ml
产品形态	Liquid
保存条件	12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料	BSP is also known as IBSP(integrin-binding sialoprotein). The protein encoded by this gene is a major structural protein of the bone matrix. Bone sialoprotein is an acidic glycoprotein of approximately 70 kD that undergoes extensive posttranslational modifications. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. The BSP gene is mapped to 4q22.1.
研究类别	1. Duncan EL, et al. Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. PLoS Genet, 2011 Apr.2. Gordon JA, et al. Bone sialoprotein stimulates focal adhesion-related signaling pathways: role in migration and survival of breast and prostate cancer cells. J Cell Biochem, 2009 Aug 15.

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博士德.BA2329 Anti-IBSP Antibody 50ul博士德

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