货品编号： Biolegend.103112

品牌： Biolegend

品名： APC anti-mouse CD45

规格： 100ul

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a

member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature

erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5,

and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal

transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell

type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.