货品编号： Biolegend.123111-25ug

品牌： Biolegend

品名： PE/Cyanine5 anti-mouse F4/80 Antibody

规格： 25ug

F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane

7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is

expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus

and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch),

Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells.

The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+

T cells-mediated peripheral tolerance.