货品编号： Bioss.bs-14477R

品牌： Bioss

品名： Rabbit Anti-Dystrophin antibody

规格： 100ul

Dystotelin (DYTN) is a 578 amino acid cell membrane protein that contains one ZZ-type zinc finger. The gene that encodes

dystrotelin maps to human chromosome 2, which makes up approximately 8% of the human genome and contains 237

million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin

icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia

is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is related to mutations

in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives

credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes,

which are still present in modern day apes.