货品编号: 博奥森.bs-0413R
品牌: 博奥森
品名: 免疫组化抗体
规格: 100UL
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when
cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III,
IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of
atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
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