bioss.bs-11306R 磷酸乙醇胺转移酶A抗体 50ulBioss-耗材-金山科研平台 Thermo Fisher官网Nunc、QSP、Nalgene、Invitrogen、Gibco耗材试剂授权一级代理

bioss.bs-11306R 磷酸乙醇胺转移酶A抗体 50ulBioss

货品编号： bioss.bs-11306R

品牌： bioss

品名：磷酸乙醇胺转移酶A抗体

规格： 50ul

产品介绍

Increase in fetal surfactant synthesis and lung maturity is caused by the glucocorticoidal induction of enzymes required for phosphatidylcholine synthesis towards the end of gestation (1). The regulation of gestational age-dependent induction of phosphatidylcholine synthesis by glucocorticoids is still unclear (1). The rate-controlling enzyme in the phosphatidylcholine biosynthetic pathway is CTP-phosphocholine cytidylyltransferase A (CCT A) (2–4). In cultured eukaryotic cells, this enzyme is essential for survival (3). The alpha isoform is located in the nucleus and is regulated by reversible phosphorylation and membrane association (3). There is significant identity between the alpha-helical membrane-binding domains of CCT A and soybean oleosin (2). Expressed CCT A has lipid-dependent cytidylyltransferase activity (5). The gene which encodes CCT A maps to human chromosome 3q (4).Function:Controls phosphatidylcholine synthesis.Subunit:Homodimer.Subcellular Location:Cytoplasm; cytosol. Membrane. It can interconvert between an inactive cytosolic form and an active membrane-bound form.Post-translational modifications:The serine residues of the C-terminus are phosphorylated. The inactive soluble form is stabilized by phosphorylation, the active membrane bound form is promoted by anionic lipids or diacylglycerol, and is stabilized by dephosphorylation.Similarity:Belongs to the cytidylyltransferase family.SWISS:P49585Gene ID:5130Database links:

Entrez Gene: 5130Human

Entrez Gene: 13026Mouse

Omim: 123695Human

SwissProt: P49585Human

SwissProt: P49586Mouse

Unigene: 135997Human

Unigene: 98775Mouse

Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片

Paraformaldehyde-fixed, paraffin embedded (Mouse colon); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PCYT1A) Polyclonal Antibody, Unconjugated (bs-11306R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (Human stomach carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PCYT1A) Polyclonal Antibody, Unconjugated (bs-11306R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (Human breast carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PCYT1A) Polyclonal Antibody, Unconjugated (bs-11306R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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bioss.bs-11306R 磷酸乙醇胺转移酶A抗体 50ulBioss

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