货品编号: Bioss.bs-2469R
品牌: Bioss
品名: Rabbit Anti-PERK antibody
规格: 50ul
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its
inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane
protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this
gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Jan 2010]
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