产品英文名称:Thiazovivin

产品中文名称:Thiazovivin

Thiazovivin Rho相关激酶抑制剂 产品介绍:

Thiazovivin, N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide,是Rho相关激酶的抑制剂.它能够保护人胚胎干细胞在缺失ECM环境中存活,主要是通过调节E-钙粘附素来调节细胞间的相互作用.Thiazovivin 结合了TGF-beta受体抑制因子和MEK激酶,能够显著提高重组效率.Thiazovivin 使用LC/MS层析法检测,纯度大于99%.生物活性已通过在无血清培养基上培养人iPS细胞得到验证.

Thiazovivin Rho相关激酶抑制剂 产品特性:

» Thiazovivin 能够抑制Rho相关激酶的活性

» 通过LC/MS检测,纯度大于99%

» 生物活性:在无血清培养基上培养人iPS细胞得到验证

» Thiazovivin 只限于科学应用,不能用于人体

Thiazovivin 产品英文简述:

Thiazovivin, N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide, is a selective inhibitor of Rho-associated kinase (ROCK). It protects human ES cells from death in the absence of ECM by regulating E-cadherin mediated cell-cell interaction. Thiazovivin, in combination with inhibitors of the TGF-beta receptor and the MEK kinases, improves reprogramming efficiency dramatically.

• Purity:Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.

• Biological Activity:Tested active for culturing human iPS cells in serum-free medium on Matrigel coated plates.