代理SAG, SMO agonist 1mg Hedgehog家族 现货


产品英文名称:SAG, SMO agonist

产品中文名称:SAG SMO激动剂

SAG 产品英文简述:

SAG is a highly potent agonist of SMO (smoothened). This small molecule compound activates the hedgehog pathway by directly binding to SMO. Note: in the Gli-1 reporter gene assay, SAG acts as an activator at concentrations from approximately 1 nM to 1 uM, but as an inhibitor at concentrations high than 1 uM.

• Purity: Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.

• Biological Activity: In a cell-based assay measuring the activation of the Gli-1 reporter gene, this compound gives EC50 of 5-15 nM.

• This compound is potentially toxic. Handle with extreme care

• For Research Use Only. Not for Use in Humans.

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