产品英文名称：Human Mesenchymal Stem Cell Lineage Antibody Cocktail

产品中文名称: 人间充质干细胞谱系抗体混合物

BD Human Mesenchymal Stem Cell Lineage Antibody Cocktail 的物质组成

PE hMSC Negative Cocktail (CD34, CD11b, CD19, CD45, HLA-DR), PE Isotype Control Cocktail (mouse IgG1, k, mouse IgG2a, k.

BD 人间充质干细胞谱系抗体混合物的应用

混合识别潜在的污染物。(Cocktail to identify potential contaminants.)

BD Human Mesenchymal Stem Cell Lineage Antibody Cocktail 的保存条件

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.

BD Human Mesenchymal Stem Cell Lineage Antibody Cocktail 的英文描述

Human multipotent mesenchymal stromal cells (MSCs), also referred to as mesenchymal stem cells, are a rare population of adult stem cells that can be isolated from a variety of tissues. MSCs that have been isolated from bone marrow and subsequently cultured can differentiate to a variety of cell types, most notably adipocytes, osteocytes and chondrocytes. MSCs also have immunomodulatory effects in vivo and in vitro. In 2006, the International Society for Cellular Therapy (ISCT) proposed a cell surface marker panel for the minimal identification of human MSCs derived from bone marrow. Under this recommendation MSCs should be positive for CD73, CD90, and CD105, but be negative for CD34, CD45, CD11b or CD14, CD19 or CD79α, and HLA-DR. MSCs are also known to express numerous cell surface markers such as CD44, CD29, CD200, CD166, CD146 and CD271. This lineage set includes the set of ISCT negative markers as a cocktail and also a corresponding isotype control cocktail.