产品英文名称：EED antibody (mAb)

产品中文名称：EED 抗体 (mAb))

Active Motif EED单克隆抗体 61203产品英文描述：

Background:

EED (extraembryonic ectoderm) is a component of the Polycomb group (PcG) multiprotein complex PRC2. The PRC2 complex also contains EZH2 and SUZ12 and is recruited to Polycomb response elements and results in the methylation of histone H3 and lysine 27 and the silencing of gene expression. PRC2 initiates repression of the Hox genes during development and is involved in the maintenance of stem cell pluripotency. EED is a member of the superfamily of WD-40 repeat protein family and is required for PRC2-mediated H3K27 methylation. The PRC2 complex may also recruit platform DNMTs, thereby linking two systems of epigenetic repression.

Immunogen:

This EED antibody was raised against full-length recombinant human EED protein.

Buffer:

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.Sodium azide is highly toxic.

Application Notes:

This EED antibody has been validated for use in chromatin IP (ChIP, 4 μl per ChIP), ChIP-Seq & ChIP-chip (4 μl each), immunohistochemistry (2 - 8 μg/ml) and has been reported to work in Western blotting.

Storage and Guarantee:

Antibodies in solution can be stored at -20°C for 2 years.Avoid repeated freeze/thaw cycles and keep on ice when not in storage. This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Active Motif EED单克隆抗体 61203产品产品介绍：