Sigma R2625-50mg,Retinoic acid,维甲酸,含量:≥98%(HPLC),粉,规格:50mg,安瓿瓶装Sigma-Aldrich


货品编号: Sigma.R2625-50mg

品牌: Sigma-Aldrich

包装:50mg (安瓿瓶装)

别名:ATRA Tretinoin Vitamin A acid 全反式维甲酸

经验分子式(希尔表示法):C20H28O2

分子量:300.44

Biochem/physiol Actions

all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®,1280), a biologically annotated collection of high-quality, ready-to-screen compounds.

assay ≥98% (HPLC)
form powder
color yellow
mp 180-181°C(lit.)
storage temp. −20°C
Gene Information human ...RARA(5914),RARB(5915),RARG(5916),RXRA(6256),RXRB(6257),RXRG(6258)mouse ...Rara(19401),Rarb(218772),Rarg(19411),Rxrb(20182)
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