货品编号： Cayman.16069

品牌： Cayman

品名： Cytarabine

规格： 500mg

产品描述

Cytarabine is a nucleoside analog that differs from cytosine by the presence of a hydroxyl group at the 2’ position of the sugar residue.

It is triphosphorylated in vivo to produce ara-CTP, a competitive inhibitor of DNA polymerases α and β (Kis = 4 and 32 µM, respectively).1,2,3

At low concentrations, ara-CTP is incorporated into DNA, slowing but not stopping DNA synthesis.4 Cytarabine is effective in the treatment

of leukemias.4 It can also have antiviral actions on certain types of viruses.5