货品编号： Sigma.349631

品牌： Sigma

品名： dimethyl αKG

Application Dimethyl 2-oxoglutarate may be used to synthesize the conformationally constrained PNA (peptide nucleic acid) -monomer

capable of binding thymine in a triplex motif.[2] It may be used in the synthesis of 4-aryl kainic acid analogs, via highly

stereoselective Michael addition reaction with nitrostyrene.

General description Dimethyl 2-oxoglutarate is a key intermediate formed during the Krebs cycle and an important nitrogen transporter in the

biological metabolic pathways.[1] The electrochemical behavior of dimethyl-2-oxoglutarate has been investigated by cyclic

voltammetry, square wave voltammetry and differential pulse voltammetry using a glassy carbon electrode.