Sigma P4394-100mg 顺铂 100mgSigma-Aldrich-耗材-金山科研平台 Thermo Fisher官网Nunc、QSP、Nalgene、Invitrogen、Gibco耗材试剂授权一级代理

Sigma P4394-100mg 顺铂 100mgSigma-Aldrich

货品编号： Sigma.P4394-100mg

品牌： Sigma

品名：顺铂

规格： 100mg

产品描述

强效的铂基抗肿瘤剂。与 DNA 二核苷酸 d(pGpG) 形成细胞毒性加合物，诱导链内交联。

Potent chemoimmunotherapeutic drug; stimulates the immune responses by activating macrophages and other cells of the

immune system. Cisplatin-treated macrophages show increased antigen presentation function in vitro. Treatment increased

cellular NF-κB content and translocation in macrophages. Cisplatin effects are regulated by kinases, phosphatases, and

Ca2+/calmodulin. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand crosslinks.

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Sigma P4394-100mg 顺铂 100mgSigma-Aldrich

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