Invitrogen EN0525 DNase I, RNase-free (supplied with MnCl2) (1 U/µL) 1,000 unitsInvitrogen


货品编号: Invitrogen.EN0525 品牌: Invitrogen 品名: DNase I, RNase-free (supplied with MnCl2) 规格:1,000 units

产品描述:

Thermo Scientific DNase I, RNase-free is an endonuclease that digests single- and double-stranded DNA. It hydrolyzes phosphodiester bonds

producing mono- andoligodeoxyribonucleotides with 5'-phosphate and 3'-OH groups. The enzyme activity is strictly dependent on Ca2+ and is activated by Mg2+ or Mn2+ ions. In the presence of Mg2+, DNase I cleaves each strand of dsDNA independently in a statistically random fashion. In the presence of Mn2+, the

enzyme cleaves bothDNA strands at approximately the same site, producing DNA fragments with blunt-ends or with overhang termini of only

one or two nucleotides.

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