货品编号： Sigma.I5879-100mg 品牌： Sigma 品名： 3-异丁基-1-甲基黄嘌呤 规格： 100mg
产品描述：
Biochem/physiol Actions Non-specific inhibitor of cAMP and cGMP phosphodiesterases. The increase in cAMP level as a result of phosphodiesterase inhibition
by IBMX activates PKA leading to decreased proliferation, increased differentiation, and induction of apoptosis. IBMX inhibits
phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50: 1.3 μM). Also
serves as an adenosine receptor antagonist. Shown to inhibit ion channels in the neuromuscular junction, GH3 cells, and vascular smooth
muscle cells. Induces calcium release from intracellular stores in sensory neurons.
Features and Benefits This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated
collection of high-quality, ready-to-screen compounds. Click here to learn more.
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