Lumiprobe荧光素的替代染料–菁染料

知识背景：

菁染料是性能优良的可代替荧光素的染料，摩尔吸光系数高，其琥珀酰亚胺酯是最常用的脂肪氨基标记试剂，广泛用于蛋白、抗体、核酸及其他生物分子的标记和检测。通过改变次甲基链的长度, 可改变其荧光发射波长，每增加一个双键，按照Huoffman 规则正好红移约100nm。

菁染料Cy3 和Cy5 已成为基因芯片的首选荧光标记物; 另外,Cy5, Cy5.5 和Cy7 的吸收在近红外区背景非常低，是荧光强度最高、最稳定的长波长染料。特别适合于活体小动物体内成像代替放射性元素。

但由于菁染料, 尤其是不对称菁染料的合成副反应多, 副产物极性相近, 产物的分离提纯相当困难。菁染料特别是水溶性菁染料分子极性大, 分离提纯越加困难。

应用领域：

广泛应用于多肽，蛋白，核苷酸及其他生物分子的标记和检测。

产品列表：

货号 产品名称 产品规格 1A041 Cyanine2 NHS ester minimal dye 5 nmol,10nmol,25nmol A10B0 Cyanine3 alkyne 1 mg,10mg,25mg,50mg 110C0 Cyanine3 amine 1 mg,10mg,25mg,50mg 31030 Cyanine3 azide 100ul,500ul,1ml A1030 Cyanine3 azide 1 mg,10mg,25mg,50mg 61090 Cyanine3 carboxylic acid 1 mg,10mg,25mg,50mg 11070 Cyanine3 hydrazide 1 mg,10mg,25mg,50mg 61080 Cyanine3 maleimide 1 mg,10mg,25mg,50mg 11020 Cyanine3 NHS ester 1 mg,10mg,25mg,50mg 3B041 Cyanine3 NHS ester minimal dye 1 mg,10mg,25mg,50mg 12030 Cyanine3.5 azide 1 mg,10mg,25mg,50mg A2030 Cyanine3.5 azide 1 mg,10mg,25mg,50mg 12090 Cyanine3.5 carboxylic acid 1 mg,10mg,25mg,50mg 62020 Cyanine3.5 NHS ester 1 mg,10mg,25mg,50mg A30B0 Cyanine5 alkyne 1 mg,10mg,25mg,50mg 630C0 Cyanine5 amine 1 mg,10mg,25mg,50mg 13030 Cyanine5 azide 100ul,500ul,1ml E3030 Cyanine5 azide 1 mg,10mg,25mg,50mg 130A0 Cyanine5 Boc-hydrazide 1 mg,10mg,25mg,50mg 63090 Cyanine5 carboxylic acid 1 mg,10mg,25mg,50mg 13070 Cyanine5 hydrazide 1 mg,10mg,25mg,50mg 63080 Cyanine5 maleimide 1 mg,10mg,25mg,50mg 13020 Cyanine5 NHS ester 1 mg,10mg,25mg,50mg 3C041 Cyanine5 NHS ester minimal dye 1 mg,10mg,25mg,50mg A70B0 Cyanine5.5 alkyne 1 mg,10mg,25mg,50mg 670C0 Cyanine5.5 amine 1 mg,10mg,25mg,50mg 14030 Cyanine5.5 azide 100ul,500ul,1ml E4030 Cyanine5.5 azide 1 mg,10mg,25mg,50mg 17090 Cyanine5.5 carboxylic acid 1 mg,10mg,25mg,50mg 67070 Cyanine5.5 hydrazide 1 mg,10mg,25mg,50mg 17080 Cyanine5.5 maleimide 1 mg,10mg,25mg,50mg 67020 Cyanine5.5 NHS ester 1 mg,10mg,25mg,50mg A50B0 Cyanine7 alkyne 1 mg,10mg,25mg,50mg 650C0 Cyanine7 amine 1 mg,10mg,25mg,50mg 15030 Cyanine7 azide 100ul,500ul,1ml E5030 Cyanine7 azide 1 mg,10mg,25mg,50mg 15090 Cyanine7 carboxylic acid 1 mg,10mg,25mg,50mg 65070 Cyanine7 hydrazide 1 mg,10mg,25mg,50mg 15080 Cyanine7 maleimide 1 mg,10mg,25mg,50mg 65020 Cyanine7 NHS ester 1 mg,10mg,25mg,50mg A60B0 Cyanine7.5 alkyne 1 mg,10mg,25mg,50mg 660C0 Cyanine7.5 amine 1 mg,10mg,25mg,50mg 16030 Cyanine7.5 azide 100ul,500ul,1ml 66090 Cyanine7.5 carboxylic acid 1 mg,10mg,25mg,50mg 16070 Cyanine7.5 hydrazide 1 mg,10mg,25mg,50mg 66080 Cyanine7.5 maleimide 1 mg,10mg,25mg,50mg 16020 Cyanine7.5 NHS ester 1 mg,10mg,25mg,50mg