产品描述：

TCS-OX2-29 is a potent and selective OX2 receptor antagonist with IC50 of 40 nM. Displays >250-fold selectivity for

OX2 over OX1. target: OX2 IC 50: 40 nM In vitro:TCS-OX2-29 shows selectivity for ion channels, and transporters

(<30% inhibition at 10 μM), which includes G-protein coupled receptors associated with food intake including galanin

and neuripeptide Y. [1] TCS-OX2-29 Inhibits orexin A induced IP3 accumulation and ERK1/2 phosphorylation in CHO

cells transfected with the OX2 receptor.