货品编号： Thermo.14-5698-80 品牌：Thermo 品名：Anti-Mouse/Rat Ki-67 Purified 25ug 规格：25ug 产品描述：

Description: The monoclonal antibody SolA15 recognizes mouse and rat Ki-67, a 300 kDa nuclear protein.

Ki-67 is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting

cells (G0). Ki-67 is detected within the nucleus during interphase but redistributes to the chromosomes during

mitosis. Ki-67 is used as a marker for determining the growth fraction of a given population of cells. In studies

of tumor cells, the "Ki-67 labeling index" refers to the number of Ki-67 positive cells within the population and

this is used to predict outcome of particular cancer types. Ki-67 has been shown to interact with the DNA-bound

protein chromobox protein homolog 3 (CBX3) (heterochromatin).

The SolA15 antibody also recognizes human, non-human primate and canine Ki-67.

Applications Reported: This SolA15 antibody has been reported for use in immunohistochemical staining of

formalin-fixed paraffin embedded (FFPE) tissue sections and frozen (paraformaldehyde fixed) sections and

immunocytochemistry (ICC).

Applications Tested: This SolA15 antibody has been tested by immunohistochemistry on formalin-fixed paraffin

embedded mouse skin with high or low pH antigen retrieval and immunocytochemistry on fixed and permeabilized

C2C12 cells at less than or equal to 5 ug/mL. It is recommended that this antibody be carefully titrated for optimal

performance in the assay of interest.