货品编号： Bioss.bs-21231R

品牌：Bioss

品名：Rabbit Anti-SLC25A33 antibody

规格：200ul

产品描述：

background: SLC25A33 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al.,

2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]

Function: Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria (PubMed:25320081).

Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport

mechanism (PubMed:25320081). Also transports guanine but not adenine (deoxy)nucleotides (PubMed:25320081). Is

inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury

dichloride, mersalyl acid, p-hydroxymercuribenzoate) (PubMed:25320081). Participates in mitochondrial genome

maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration (PubMed:20453889).

Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and

transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control

of mitochondrial ROS production (PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and

may associate with mitochondrial oxidative phosphorylation (PubMed:14715278).