货品编号： Bioss.bs-0169R-100ul

品牌：博奥森

品名：Caspase-1 P10天冬氨酸-胱氨酸特异性蛋白酶家族抗体

规格：100ul

产品描述：

background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation

of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo

proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active

enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a

cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce

cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the

pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms.