博奥森.bs-13787R 19号染色体开放阅读框51抗体 100ul Bioss


货品编号: 博奥森.bs-13787R 品牌:博奥森 品名:19号染色体开放阅读框51抗体 规格:100ul

产品描述: background: C19orf51 is a 541 amino acid protein that exists as three alternatively spliced isoforms and are encoded by a gene located

on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human

genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene

density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including

the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes

for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke

disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations

with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-

oncogene BCL3.

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