货品编号： Gibco.42-6500 品牌：Gibco 品名：TBX5 Polyclonal Antibody 规格：100ug

产品描述： Background/Target Information This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box.

T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to

related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in

heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a

developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been

described for this gene.