货品编号： thermo.11-0042-82 品牌： thermo 品名：CD4 Monoclonal Antibody (RM4-5), FITC, eBioscience™ 规格：100ug

产品描述：

Description: The RM4-5 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor

expressed by a majority of thymocytes, subpopulation of mature T cells and dendritic cells. CD4 binds to MHC class

II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal

functioning of mature T cells. In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail.

Binding of RM4-5 is blocked by GK1.5.

Applications Reported: The RM4-5 antibody has been reported for use in flow cytometric analysis.

Applications Tested: The RM4-5 antibody has been tested by flow cytometric analysis of mouse thymocytes and

splenocytes. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody

that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from

10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.

Filtration: 0.2 µm post-manufacturing filtered.