货品编号： Biolegend.368508 品牌： Biolegend 品名：FITC anti-human CD45 Antibody 规格：100 tests

产品描述：

CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and

T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, excepterythrocytes or

platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation,

cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by

dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with

lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind

galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.