货品编号: thermo.11-5773-82 品牌: thermo 品名:FOXP3 Monoclonal Antibody (FJK-16s), FITC, eBioscience™ 规格:100ug
产品描述:
Description: The FJK-16s antibody reacts with mouse, rat, dog, porcine, bovine and cat Foxp3 also known
as FORKHEAD BOX P3, SCURFIN, and JM2; cross reactivity of this antibody to other proteins has not been
determined. Foxp3, a 49-55 kDa protein, is a member of the forkhead/winged-helix family of transcriptional
regulators, and was identified as the gene defective in 'scurfy' (sf) mice. Constitutive high expression of foxP3
mRNA has been shown in CD4+CD25+ regulatory T cells (Treg cells), and ectopic expression of foxp3 in
CD4+CD25- cells imparts a Treg phenotype in these cells.
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