货品编号： 阿拉丁.C131116-1mg 品牌：阿拉丁 品名： Calcein, AM 规格：1mg

产品描述：

Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein ,

which is an extremely fluorescent and negatively charged molecule. The probe can be used to stain living cells and has been

observed to fluoresce bright green in cytoplasmic Schwann cells. Calcein-AM has been reported to be a neutral substrate for

Mdr (P-glycoprotein (Pgp) and multidrug resistance protein (MRP)) and has been used in flow cytometry studies to analyze the

function of P-gp and MRP. Studies suggest that Calcein-AM can be used to detect MDR mediated resistance and to be transported

by PGP from the plasma membrane. Mitochondrial permeability research has utilized Calcein as a cytosolic fluorophore. Has been

used as a cytosolic fluorophore in mitochondrial permeability studies to image pore transition.