货品编号： Bioss.bs-15353R 品牌： Bioss 品名：Rabbit Anti-GPCR EX33 antibody 规格： 100ul 储存条件：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room

temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in

sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

产品描述：

background: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical

receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular

second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse

biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many

pathological conditions. G protein receptor 84 (GPR84), a member of the GCPR 1 family, is an orphan GCPR

expressed in bone marrow, brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, lung and

peripheral blood leukocytes. In activated T cells, GPR84 regulates early interleukin-4 (IL-4) gene expression