货品编号: 博奥森.bs-2353R 品牌:博奥森 品名:肥大细胞类糜蛋白酶1抗体 规格:100ul
产品描述:
background: This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast
cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion,
and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting
enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been
implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus,
this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding
other proteases. [provided by RefSeq, Jul 2008]
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