产品描述： background: P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with

secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad

substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules),

liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the

normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal

tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon,

endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas.