博奥森.bs-5785R Rabbit Anti-ARHGAP24 antibody 100ul Bioss


货品编号: 博奥森.bs-5785R 品牌:博奥森 品名: Rabbit Anti-ARHGAP24 antibody 规格:100ul

产品描述: ARHGAP24 is a rho GTPase-activating protein involved in cell polarity, cell morphology and

cytoskeletal organization. It acts as a GTPase activator for the Rac-type GTPase by converting

it to an inactive GDP-bound state. It controls actin remodeling by inactivating Rac downstream

of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular

polarity. There are five different isoforms.Isoform 1 is widely expressed with a higher level in kidney.

Isoform 2 is mainly expressed in endothelial cells and is involved in modulation of angiogenesis.

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