货品编号: 博奥森.bs-23926R
品牌:博奥森
品名:Rabbit Anti-TRPV1 antibody
规格:50ul
产品描述:
background: The detection of noxious stimuli (chemical, mechanical, or thermal) occurs predominantly at the
peripheral terminals of primary afferent neurons. This information is ultimately transmitted to the
central nervous system to evoke a perception of pain which initiates appropriate protective reflexes.
The receptor for capsaicin, VR1 (vanilloid receptor 1; TRPV1 is a nonselective cation channel that
resembles members of the transient receptor potential (TRP) family of ion channels. The vanilloid
receptor 1 protein functions both as a receptor for capsaicin and a transducter of noxious thermal
stimuli. VR1 protein is localized to small-diameter sensory neurons within the dorsal root ganglia
and nerve terminals in the dorsal horn.
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