产品描述： background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix

metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its

inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range

of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to

many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that

this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is

transcribed in the opposite direction. [provided by RefSeq].