货品编号： 博奥森.bs-11093R 品牌：博奥森 品名：Rabbit Anti-Myelin PLP antibody 规格：100ul

产品描述： background: PLP is a major constituent of myelin. The two isoforms of the myelin proteolipid protein, PLP and DM20, are very

hydrophobic integral membrane proteins that account for about half of the protein content of adult CNS myelin. A

mutation in the gene which encodes PLP is linked to Pelizaeus-Merzbacher disease (PMD), a chronic infantile type

of diffuse cerebral sclerosis. The gene which encodes PLP maps to human chromosome Xq22. The glycoprotein

zero (also designated P-zero or myelin peripheral protein) is the primary structural protein of peripheral myelin, and

accounts for more than 50% of the protein present in the peripheral nerve sheath. Zero is an integral membrane

glycoprotein. Expression of zero is restricted to Schwann cells. The gene which encodes zero maps to human

chromosome 1q22. PMP22 (peripheral myelin protein 22) is a growth-regulated membrane protein which is

expressed by Schwann cells and is localized primarily in compact peripheral nervous system myelin. The gene

which encodes PMP22 maps to human chromosome 17p11.2.