产品描述： background: Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to

mediate the attachment, migration, and organization of cells into tissues during embryonic development

by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta,

and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene

encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4

(s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient

muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.