货品编号： biolegend.109832 品牌：biolegend 品名：Brilliant Violet 421™ anti-mouse CD45.2 Antibody

产品描述： Description CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR,

BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45,

a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on

all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse

that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation

and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1,

CD2, CD3, CD4, TCR, CD22, and Thy-1.